As shown in table 2, the mean value of alt of normal animals was 44. Aerial parts, methanol, aqueous 100, 200, and 400 mgkg, ccl4. In vitro study of antiamoebic activity of methanol extracts. Chloroform extract of argemone mexicana 100 and 200 mgkg body weight was administered daily in experimental animals. Medicinal plants possessed hepatoprotective activity 28 stress imposed by tbhp in the hepatic tissues as evidenced by marked improvement in the antioxidant status and suppressing lipid peroxide levels. A boon to medicinal and pharmacological approaches in current scenario nature is gods gift to human beings. The present study aims to determine the hepatoprotective effect of mardiproduced virgin coconut oils, prepared by dried or fermentedprocessed methods, using the paracetamolinduced liver damage in rats. Medicinal plants possessed hepatoprotective activity. Antifungal and anticancer potential of argemone mexicana l. Bixa orellana, argemone mexicana, physalis minima, caesalpinia bonduc belonging to different family were studied for hepatoprotective activity against swiss albino rats with liver damage induced by cc14. Deccan school of pharmacy 1, hyderabad, andhra pradesh, india. This extract exerted a significant hepatoprotection of tertbuty. The effects of 2 concentrations 15 and 30% of ethanolic argemone ochroleuca sweet papaveraceae extracts were determined on the feeding. Choleretic effects, often mentioned in traditional indications, have not been confirmed in rats.
Pdf hepatoprotective activity of some medicinal plants in sudan. Oxidative damage of plasma proteins and lipids in epidemic dropsy. One study has evaluated the role of egcg, the main green tea catechin, in the hepatoprotective effect of green tea chen et al. Argemone is from the greek argena, meaning cataract of the eye, and was the name used in the first century ad by the classical authors dioscorides ad 4090 and pliny ad 2379 for some spiny poppies, the juice of which was supposedly a cure for cataract. May 01, 2014 further studies are in progress to identify the active components responsible for the hepatoprotective and antioxidant activity of a. Argemone mexicana, biological activity, papaveraceae. Antistress and antiallergic effect of argemone mexicana stem in asthma. Hepatoprotective activity of argimone maxicana and acacia arabica. Liver, the largest gland functioning as an organ of storage, manufacturing and biotransformation is a vulnerable target for injury. Yellow colored blooms of argemone mexicana and turnera. Argemone mexicana is one of the most effective plants used. The extracts were given at different doses, 100, 200, and 400.
Argemone mexicana and its potential antihepatitis promises. Histological observation also confirms liver damage. Pdf hepatoprotective activity of some medicinal plants. Argemone mexicana is native in mexico and the west indies, but has become pantropical after accidental introduction or introduction as an ornamental. It is a major weed of a number of crops in the tropics and warm temperate regions and is persistent as it produces a seed bank. Antimicrobial and antifungal activities of methanol extract of. Mainly cholesterol or lecithin rich dietary fats enhances the risk of cholelithiasis while omega3omega6 fatty acids reduce the risk of bile lithogenicity and play hepatoprotective role in primary, secondary and late onset. Antioxidant and anti proliferative activities of smilax zeylanica root and rhizome extract against l.
Hepatoprotective effect of combination of 6, 7 and silymarin with the. Argemone is a genus of flowering plants in the family papaveraceae. An external file that holds a picture, illustration, etc. Dcfhtoxicatedcellswere recovered to about 100% with 100. Flowering time is all rou nutritionally poor soil and also prefers acid, neutral and basic alkaline soils rastogi r. For that, the plant argemone mexicana is a boon to the human being as it has a. The protective effects of the aqueous extract of argemone mexicana whole plant. Cyclea peltata cyclea peltata possess the potent diuretic activity. Hepatoprotective activity was explored by testing the effect of sample drug against ccl 4induced liver injury in rats.
Invasive species are considered as one of the major threats to ecosystems worldwide. Top pdf argemone mexicana were compiled by 1library. Evaluation of the effectiveness of piper cubeba extract in. Top pdf antimycobacterial potentiality of leaves and stem. The results of this study strongly indicated that aerial parts of a. Neuropharmacological study of argemone mexicana linn. Sep 19, 20 medicinal use of satyanashi or argemone mexicana prickly poppy know about argemone mexicana botanical description, medicinal properties, medicinal uses in ayurveda, its health benefits, dosage, contraindications and sideeffect of different parts of this plant. Hepatoprotective activity of argemone mexicana linn against toxic effects of. Plant contains a high amount of medicinal value which shows activity against rculosis. Hepatoprotective activity of aqueous methanolic extracts of aerial parts of abutilon bidentatum on carbon tetra chloride ccl4 and paracetamol induced liver damage in rabbits.
A boon to medicinal and pharmacological approaches in current scenario volume. Hepatoprotective activity of 7 is comparable with the standard drug silymarin in reducing the elevated liver enzymes and restoring normal appearance of hepatocytes. The seed showed oil content of 35% and protein content of 24%. Top pdf antimycobacterial potentiality of leaves and. Pdf toxicity study for argemone mexicana l world journal. During last few decades, there has been increasing interest in the study of medicinal properties of this plant and it is reported for. Natural products are a source of new chemical diversity and are the choice of todays world. Hepatoprotective activity of plant argemone mexicana linn against carbon tetrachloride ccl4 induced hepatotoxicity in rats.
Evaluation of the antiicterus effect of crude powdered leaf. Hepatoprotective activity of stem bark extract of mangifera indica l. The authors suggested that the hepatoprotective effects of green tea may be partly due to the chelating activity of green tea extract and the increased antioxidant enzyme activities. Pdf hepatoprotective activity of methanol extract of some. Finally, significant and dosedependent antiinflammatory effects were obtained on an acute inflammatory process carrageenaninduced edema test in. The damage in hepatic microsomal membrane causes loss of activity of. The main objective of the work was to evaluate the use of argemone m exicana am leaves for safety and efficacy in the treatment of asthma. The hepatic injury was achieved by injection of ccl 4 3 mlkg s. Nauclea latifolia and argemone mexicana, have been used in traditional medicine for the therapy of jaundice sourabie et al. During last few decades, there has been increasing interest in the study of medicinal properties of this plant and it is reported for antimicrobial, antidiabetic, antioxidant and hepatoprotective activity. Research article international journal of current research.
Acetaminophen produced 100% mortality at a dose of 1 gkg in mice while pretreatment of animals with plant extract 500 mgkg reduced the death rate to 30%. Hepatoprotective and antiinflammatory effects of a. The antiasthmatic activity of the extract by using different concentraton of methanolic extract at 500, and 1500 gml was evaluated in isolated goat tracheal chain preparations by using standard drug histamine. Evaluation of the antiicterus effect of crude powdered. Hepatoprotective drugs from plants indigenous to india. These are traditionally treated by medicinal plants especially in rural areas. Phytochemical analysis and bioactivities of argemone mexicana. The present study aimed to characterize the chemical composition of the essential oil eo from the invasive plant argemone ochroleuca sweet, collected from saudi arabia, as well as. Hepatoprotective activity of the 80% methanolic extract of r. Papaveraceae, commonly known as mexican poppy is used in rural areas of mexico as a medicinal plant. The hepatoprotective efficacy of chloroform extract of argemone mexicana 100 and 200 mgkg was investigated against paracetamolinduced hepatotoxicity. Medicinal plants possessed hepatoprotective activity through many mechanisms, included antioxidant properties of medicinal plants, enhancement of antioxidant defense superoxid dismutase, catalase and glutathione peroxidase activity 12, reduced peroxidation34.
In all test model systems, conditions for liver damage are implemented and an attempt is made to counteract this toxicosis with the substancepreparation under test. Monographycal survey of pharmacological potentials of. Intrinsic evaluation of antiurolithiatic capacity of argemone mexicana l. Dried hydroalcoholic extract of peumus boldus monimiaceae has been evaluated for hepatoprotective, choleretic and antiinflammatory effects in mice and rats, in order to validate or to invalidate traditional therapeutic indications. International journal of pharmaceutical sciences and research, 54, 1240. Although invasive plants are regarded as a foe, they could be considered as natural resources for valuable bioactive compounds. Argemone mexicana is native in mexico and the west indies, but has become pantropical after. Argemone mexicana is an annual herb with eggshaped seed, alkaloids like berberine, protopine, protopine hydrochloride, sanguinarine, and dihydrosanguinarine with pharmacological, spasmolytic, antibacterial, antifungal, and antiprotozoal activities were isolated from the plant. Argemone mexicana is an indigenous herb commonly known as prickly poppy. The hepatoprotective activity of water and methanolic extracts of argemone mexicana l.
Epidemic dropsy is a form of edema of extremities due to poisoning by argemone mexicana. It contains 3032 species, commonly known as prickly poppies all with prickly stems, leaves and capsules 1. Argemone mexicana is noted to possess medicinal benefits in traditional system of medicine. Many studies have showed a hepatoprotective activity of r. Argemone mexicana solanaceae plant material carbontetra chloride induced. Antifungal activity of the extract was comparable to that of amphoterecinb. Pdf hepatoprotective activity and flavonoids of alchornea. Antioxidants, dpph, hepatoprotective, africa, plants, natural. Hepatoprotective effect of polyphenols rich methanolic. Rangasamy college of arts and science, tiruchengode 637215, tamilnadu, department of biochemistry, k. The methanol extracts of plant materials of some plants like casuarina equisetifolia, cajanus cajan, glycosmis pentaphylla, bixa orellana, argemone mexicana, physalis minima, caesalpinia bonduc, belonging to the different family were studied for hepatoprotective activity against swiss albino rats with liver damage induced by carbon tetrachlorideccl. Hepatoprotective activity of some medicinal plants in sudan.
Solanum nigrum is one of them with proven anticancer as well as antiinflammatory activity 5. Plants used for the treatment of icterus jaundice in central india. Parmar and others published hepatoprotective activity of some plants extract against paracetamol induced hepatotoxicity in wistar rats find, read and cite all the. Sitha institute of pharmaceutical sciences 2, hyderabad, andhra pradesh. Evaluation of the wound healing activity of the crude extract.
Download acrobat pdf file 1mb transparency document. Owning to these results, the plant has the potential to be used as a medicine against the diseases caused by free radicals. All the animals from treated acute toxicity study of argemone mexicana groups did not show any significant decrease in linn. Medicinal use of satyanashi or argemone mexicana prickly.
Hepatoprotective effects of the decoction and macerated. Phytochemical analysis and bioactivities of argemone. Hepatoprotective activity serum biochemical analysis in the pretreatment model. Nematicidal effect of the oil from the seeds of argemone mexicana. Mohammed ishaq 3 deccan school of pharmacy 1, hyderabad, andhra pradesh, india. Full text in vivo hepatoprotective and in vitro radical.
Argemone mexicana linn papaveracea is common everywhere by road sides and fields in india. The hepatoprotective activity of an aqueousmethanol extract of rubia cordifolia rubiaceae was investigated against acetaminophen and ccl 4 induced hepatic damage. Mechanisms underlying the relaxation induced by isokaempferide from a. Pdf the leaves of alchornea laxiflora have antihistamine, antiinfectious and antiinflammatory applications in ethno medicine. Hepatoprotective activity of dried and fermentedprocessed. Sharma, in bioactive food as dietary interventions for liver and gastrointestinal disease, 20 9. Antibacterial potentiality of argemone mexicana solvent. On the contrary, aqueous extracts cold and hot of a. Moreover, medicinal plants have gained popularity in the treatment of several diseases including liver. Hepatoprotective activity of extracts was evaluated. Argemone mexicana an overview sciencedirect topics. Pdf hepatoprotective activity of methanol extract of. The objective of this work was to evaluate the potential biological activity of a.
Antipyretic effect of argemone mexicana was studied by using yeast induced pyrexia method on mice. Hepatoprotective activity of argemone mexicana linn against toxic effects of carbon tetrachloride in rats. Chronic alcohol consumption, exposure to toxic chemicals and certain drugs like paracetamol, tetracycline, antitubercular drugs, chemotherapeutic agents, nsaids, damage the liver cells hepatocytes in long run. Pdf hepatoprotective activity of some plants extract. Liver diseases still represent a major health burden worldwide. Argemone mexicana l a weed with versatile medicinal and pharmacological applications.
Mar 15, 20 the hepatoprotective activity can be most easily evaluated screened with the aid of several model systems of liver damage in experimental animals. An acute toxicity study body weights for all the 14 days as compared with was carried out on argemone mexicana linn. Sitha institute of pharmaceutical sciences 2, hyderabad, andhra pradesh, india. These results confirm the dosedependent property that characterizes the crude powdered leaf of argemone mexicana linn. The results obtained were dose dependent with 500 mgkg bw, dosage of. The antioxidant activities of synthesized silver nanoparticles were. Luzia kaml, costa mf, pitombeira m, barroso vm, silveira er and canuto mk. Amoebiasis, a parasitic infection caused by entamoeba histolytica e. Argemone mexicana, papaveraceae, mexican prickly poppy, alkaloids, berberine, drug discovery. Hepatoprotective and antioxidant activity of ethanolic. The authors declare that there are no conflicts of interest. Thus, the present study was to evaluate the effectiveness of piper cubeba fruits in the amelioration of ccl 4 induced liver injuries and oxidative damage in the rodent model.
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